Azathioprine

AZATHIOPRINE – ORAL (aze-uh-THIGH-oh-preen)

COMMON BRAND NAME(S): Imuran

WARNING: Long-term use of this medication increases the risk of developing neoplasias (cancerous or noncancerous growths). Azathioprine can also cause blood disorders (e.g., leukopenia). Immediately notify your doctor if you develop unusual growths, easy bruising or bleeding, or signs of infection such as persistent sore throat or fever.

USES: Azathioprine is used to prevent rejection of transplanted organs and for cases of severe arthritis that do not respond to other therapies.

OTHER USES: This medication may also be used to treat ulcerative colitis and for other purposes as determined by your doctor.

HOW TO TAKE THIS MEDICATION: Azathioprine tablets should be taken with food or milk to prevent stomach upset. Take this medication exactly as prescribed. Do not stop taking the medication without your doctor’s approval.

SIDE EFFECTS: Nausea/vomiting, loss of appetite or diarrhea may occur. If these effects persist or worsen, notify your doctor promptly. Unlikely but report promptly: hair loss, unusual fatigue, stomach pain, joint or muscle pain, vision changes. Very unlikely but report promptly: yellowing of eyes or skin, darkened urine, unusual bleeding or bruising, unusual lumps or growths. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before you take azathioprine, tell your doctor your medical history especially if you have:

DRUG INTERACTIONS: Tell your doctor of all drugs you may use, (both prescription and nonprescription), especially of:

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, and diarrhea.

NOTES: Lab tests will be done frequently while taking this medication to monitor its effects. Do not allow anyone else to take this medication.

MISSED DOSE: If you take this once daily and miss a dose, take it as soon as remembered but not if it is almost time for the next dose. Skip the missed dose and resume regular schedule. Do not double-up the dose to catch up. If you take this several times daily and miss one dose, take it as soon as you can or double-up the very next dose. If you miss more than one dose, contact your doctor. You may need to have your dosing schedule adjusted.

STORAGE: Store at room temperature away from moisture and sunlight. Do not store in the bathroom.