Cyproterone Acetate Drug Information
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Cyproterone Acetate Drug Information

Cyproterone Acetate

Uses: For the palliative treatment of patients with advanced prostate cancer.

Uses: For the palliative treatment of patients with advanced prostate cancer.

HOW TO USE THIS MEDICATION: The usual daily dose is 200 to 300 mg (4 to 6 tablets) divided into 2 to 3 doses and taken after meals. Androcur therapy should not be discontinued when remission or improvement occurs.

Precautions: When cyproterone is used alone it has a minor effect on blood clotting factors. Cyproterone should be discontinued at the first sign of thrombophlebitis or thromboembolism, and the patient should be carefully re-evaluated if manifestations of thrombotic disorders (thrombophlebitis, cerebrovascular complications, retinal thrombosis or pulmonary embolism) occur.

sIDe effcts: The adverse events associated most frequently with the use of cyproterone are those related to the hormonal effects of the drug. These reactions usually disappear upon discontinuation of therapy or reduction of dose: increased libido, breast enlargement, breast tenderness, benign nodular hyperplasia of the breast, galactorrhea, gynecomastia, abnormal spermatozoa, impotence and inhibition of spermatogenesis.

Overdose: There have been no reports of fatal overdosage in man with cyproterone. There are no specific antidotes and treatment should be symptomatic. If oral overdosage is discovered within 2 to 3 hours, gastric lavage can safely be used if indicated.

Storage: Store at room temperature away from sunlight and moisture.