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CARBIDOPA DESCRIPTION
Carbidopa - Tablet
Carbidopa is an antidyskinetic combination used to treat Parkinson's disease. This medicine may also be used to treat other conditions as determined by your doctor.
Where Can I order Carbidopa From? Can I buy Carbidopa at Canadian Prices?
Yes, if you are from the U.S. then you can buy Carbidopa at Canadian prices. Currently we will only accept an order for Carbidopa from U.S. and Canadian residents. Both U.S. and Canadian residents require a prescription to purchase Carbidopa and when you order Carbidopa it will be delivered with express shipping.
Why is this Carbidopa prescribed?
Sinemet CR is a controlled-release tablet that may be given to help relieve the muscle stiffness, tremor, and weakness caused by Parkinson's disease. It may also be given to relieve Parkinson-like symptoms caused by encephalitis (brain fever), carbon monoxide poisoning, or manganese poisoning.Sinemet CR contains two drugs, carbidopa and levodopa. The drug that actually produces the anti-Parkinson's effect is levodopa. Carbidopa prevents vitamin B6 from destroying levodopa, thus allowing levodopa to work more efficiently.
Parkinson's drugs such as Sinemet CR relieve the symptoms of the disease, but are not a permanent cure.
Most important fact about Carbidopa
There is also a regular, non-controlled-release form of this medication, which is called Sinemet. Over a period of hours, Sinemet CR, the controlled-release form, gives a smoother release of the drug than regular Sinemet. If you have been taking regular Sinemet, be aware that you may need a somewhat higher dosage of Sinemet CR to get the same degree of relief. Your first morning dose of Sinemet CR may take as much as an hour longer to start working than your first morning dose of regular Sinemet.
How should you take Carbidopa?
Take Sinemet CR after meals, rather than before or between meals. Swallow the tablets whole without chewing or crushing them.Sinemet CR releases its ingredients slowly over a period of 4 to 6 hours. It is important to follow a careful schedule, taking your doses at the same time every day.You should not change the prescribed dosage or add another product for Parkinson's disease without first consulting your doctor.Sinemet CR works best when there is a constant amount in the blood. Try not to miss any doses, and take them at evenly spaced intervals day and night.--If you miss a dose...If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.--Storage instructions...
Store at room temperature in a tightly closed container.
What side effects may occur with Carbidopa?
Side effects from Sinemet CR cannot be anticipated. If any develop or change in intensity, inform your doctor immediately.Only your doctor can determine if it is safe for you to continue taking Sinemet CR.
More common side effects may include:
Confusion, hallucinations, nausea, uncontrollable twitching or jerking
Less common or rare side effects may include:
Abdominal or stomach pain, abnormal dreams, agitation, anemia, anxiety, back pain, bizarre breathing patterns, bleeding from stomach, blisters, blurred vision, burning sensation of tongue, chest pain, clumsiness in walking, common cold, constipation, convulsions, cough, dark saliva, dark sweat, dark urine, delusions, depression, diarrhea, dilated pupils, disorientation, dizziness, dizziness upon rising from a sitting or lying position, double vision, dream abnormalities, drooling, drowsiness, dry mouth, euphoria, eyelid twitching, faintness, falling, fatigue, fever, flatulence, fluid retention, flushing, hair loss, headache, heart attack, heart palpitations, heartburn, hiccups, high or low blood pressure, hoarseness, hot flashes, increased sex drive, increased tremor, insomnia or other sleep problems, irregular heartbeat, leg pain, locked jaw, loss of appetite, malignant melanoma, memory problems, mental changes, muscle cramps, muscle twitching, nervousness, numbness, "on-off" phenomena, paralysis of certain muscles and unwanted movement of others, paranoia, persistent erection, phlebitis (swelling of a vein), rash, rolling eyes, shortness of breath, shoulder pain, slowed physical movements, sore throat, speech impairment, stomach ulcer, suicidal tendencies, swallowing difficulties, sweating, taste changes, teeth-grinding, tingling or pins and needles, upper respiratory infection, upset stomach, urinary frequency, urinary incontinence, urinary retention, urinary tract infections, weakness, weight loss or gain, writhing or flailing movements, vomiting
Why should Carbidopa not be prescribed?
Do not take Sinemet CR if you are sensitive to or have ever had an allergic reaction to its ingredients.
Sinemet CR should not be prescribed if you have a suspicious, undiagnosed mole or a history of melanoma.
Special warnings about Carbidopa
Make sure your doctor knows if you have any of the following:
Bronchial asthma
Cardiovascular or lung disease (severe)
Endocrine (glandular) disorder
History of heart attack or heartbeat irregularity
History of active peptic ulcer
Kidney disorder
Liver disorder
Wide-angle glaucoma (pressure in the eye)Your doctor will monitor your liver, blood, kidney and heart functions during extended therapy with Sinemet CR.If you have been taking levodopa alone, you should stop taking levodopa for at least 12 hours before starting to take Sinemet CR.The carbidopa contained in Sinemet CR cannot eliminate side effects caused by levodopa. Since carbidopa helps levodopa reach your brain, Sinemet CR may, in fact, produce some levodopa side effects--particularly twitching, jerking, or writhing--sooner and at a lower dosage than levodopa alone or even regular Sinemet. If such involuntary movements develop while you are taking Sinemet CR, you may need a dosage reduction.Like levodopa, Sinemet CR may cause depression. Make sure your doctor knows if you have mental or emotional problems.Muscle rigidity, high temperature, rapid heartbeat or breathing, sweating, blood pressure changes, and mental changes may occur when Sinemet CR is reduced suddenly or discontinued. If you stop taking this medication abruptly, your doctor should monitor your condition carefully.
You may see a red, brown, or black coloration in your saliva, urine, or sweat. This is not harmful, but may stain your clothes. Too much stomach acid can interfere with absorption of the medication.
Recommended Carbidopa dosage
Your doctor will tailor your individual dosage carefully, depending on your response to previous therapy and symptoms.
ADULTS
For patients with mild to moderate symptoms, the initial recommended dose is 1 tablet of Sinemet CR taken 2 times a day.
Starting doses should be spaced out every 4 to 8 hours and then adjusted to each patient's individual response.The usual long-term dose is 2 to 8 tablets per day, taken in divided doses every 4 to 8 hours during the waking day.Higher doses (12 or more tablets per day) and shorter intervals (less than 4 hours) have been used, but are not usually recommended.When doses of Sinemet CR are given at intervals of less than 4 hours, and/or if the divided doses are not equal, it is recommended that the smaller doses be given at the end of the day.An interval of at least 3 days between dosage adjustments is recommended.Dosage adjustment of Sinemet CR may be necessary if your doctor prescribes additional medications.
CHILDREN
Use of Sinemet CR in children under 18 is not recommended.
Carbidopa Overdosage
Too much Sinemet CR may cause muscle twitches, inability to open the eyes, or other symptoms of levodopa overdosage. Like other medications, Sinemet CR taken in excess can have serious consequences. If you suspect symptoms of a Sinemet CR overdose, seek medical attention immediately.
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