The Brand Name is no longer available in Canada. Generic brand is Selegiline and is available.

 

Why is Selegiline prescribed?

Selegiline is prescribed along with Sinemet (levodopa/carbidopa) for people with Parkinson's disease. It is used when Sinemet no longer seems to be working well. Selegiline has no effect when taken by itself; it works only in combination with Larodopa (levodopa) or Sinemet. Parkinson's disease, which causes muscle rigidity and difficulty with walking and talking, involves the progressive degeneration of a particular type of nerve cell. Early on, Larodopa or Sinemet alone may alleviate the symptoms of the disease. In time, however, these medications work less well; their effectiveness seems to switch on and off at random, and the individual may begin to experience side effects such as involuntary movements and "freezing" in mid-motion.

Selegiline may be prescribed at this stage of the disease to help restore the effectiveness of Larodopa or Sinemet. When you begin to take Selegiline, you may need a reduced dosage of the other medication.

Where can I order Selegiline from? Can I buy Selegiline at Canadian Prices?

Yes, if you are from the U.S. then you can buy Selegiline at Canadian prices. Currently we will only accept an order for Selegiline from U.S. and Canadian residents. Both U.S. and Canadian residents require a prescription to purchase Selegiline and when you order Selegiline it will be delivered with express shipping.

Most important fact about Selegiline

Selegiline belongs to a class of drugs known as MAO inhibitors. These drugs can interact with certain foods--including aged cheeses and meats, pickled herring, beer, and wine--to cause a life-threatening surge in blood pressure. At the dose recommended for Selegiline, this interaction is not a problem. But for safety's sake, you may want to watch your diet; and you should never take more Selegiline than the doctor prescribed.

How should you take Selegiline

Take Selegiline and your other Parkinson's medication exactly as prescribed. --If you miss a dose...Take it as soon as you remember. If you do not remember until late afternoon or evening, skip the dose you missed and go back to your regular schedule. Never take 2 doses at once. --Storage instructions...

Store Selegiline at room temperature.

What side effects may occur with Selegiline?

Selegiline Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Selegiline.

Selegiline Side effects may include:
Abdominal pain, abnormal movements, abnormally fast walking, aches, agitation, angina (crushing chest pain), anxiety, apathy, asthma, back pain, behavior or mood changes, bleeding from the rectum, blurred vision, burning lips and mouth or throat, chills, confusion, constipation, delusions, depression, diarrhea, difficulty swallowing, disorientation, dizziness, double vision, drowsiness, dry mouth, excessive urination at night, eyelid spasm, facial grimace, facial hair, fainting, falling down, freezing, frequent urination, general feeling of illness, hair loss, hallucinations, headache, heartburn, heart palpitations, heart rhythm abnormalities, "heavy leg", high blood pressure, hollow feeling, inability to carry out purposeful movements, inability to urinate, increased or excessive sweating, increased tremor, insomnia, involuntary movements, irritability, lack of appetite, leg pain, lethargy, light-headedness upon standing up, loss of balance, low blood pressure, lower back pain, migraine, muscle cramps, nausea, nervousness, numbness in toes/fingers, overstimulation, pain over the eyes, personality change, poor appetite, rapid heartbeat, rash, restlessness (desire to keep moving), ringing in the ears, sensitivity to light, sexual problems, shortness of breath, sleep disturbance, slow heartbeat, slow urination, slowed body movements, speech problems, stiff neck, stomach and intestinal bleeding, swelling of the ankles or arms and legs, taste disturbance, tension, tiredness, twitching, urinary problems, vertigo, vivid dreams or nightmares, vomiting, weakness, weight loss

Why should Selegiline not be prescribed?

Do not take Selegiline if you are sensitive to or have ever had an allergic reaction to it. Do not take narcotic painkillers such as Demerol while you are taking Selegiline.

Special information if you are pregnant or breastfeeding when taking Selegiline

The effects of Selegiline during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Although Selegiline is not known to cause specific birth defects, it should not be taken during pregnancy unless it is clearly needed. It is not known whether Selegiline appears in breast milk. As a general rule, a nursing mother should not take any drug unless it is clearly necessary.

Recommended Selegiline dosage

ADULTS

The recommended dose of Selegiline is 10 milligrams per day divided into 2 smaller doses of 5 milligrams each, taken at breakfast and lunch. There is no evidence of additional benefit from higher doses, and they increase the risk of side effects.

CHILDREN

The use of Selegiline in children has not been evaluated.

Selegiline Overdosage

Although no specific information is available about Selegiline overdosage, it is assumed, because of chemical similarities, that the symptoms would resemble those of overdose with an MAO inhibitor antidepressant.

Symptoms of MAO inhibitor overdose may include:
Agitation, chest pain, clammy skin, coma, convulsions, dizziness, drowsiness, extremely high fever, faintness, fast and irregular pulse, hallucinations, headache (severe), high blood pressure, hyperactivity, inability to breathe, irritability, lockjaw, low blood pressure (severe), shallow breathing, spasm of the entire body, sweating

It is important to note that after a large overdose, symptoms may not appear for up to 12 hours and may not reach their full force for 24 hours or more. An overdose can be fatal. If you suspect an Selegiline overdose, seek medical attention immediately. Hospitalization is recommended, with continuous observation and monitoring for at least 2 days.

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