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Sulfasalazine is a sulfonamide used to treat ulcerative colitis, Crohn's disease, and rheumatoid arthritis. It may also be used to treat other conditions as determined by your doctor.
Why is Sulfasalazine prescribed?
Sulfasalazine, an anti-inflammatory medicine, is prescribed for the treatment of mild to moderate ulcerative colitis (a long-term, progressive bowel disease) and as an added treatment in severe ulcerative colitis (chronic inflammation and ulceration of the lining of large bowel and rectum, the main symptom of which is bloody diarrhea). This medication is also prescribed to decrease severe attacks of ulcerative colitis.
Sulfasalazine EN-tabs are prescribed for people with ulcerative colitis who cannot take the regular Sulfasalazine tablet because of symptoms of stomach and intestinal irritation such as nausea and vomiting when taking the first few doses of the drug, or for those in whom a reduction in dosage does not lessen the stomach or intestinal side effects. The EN-tabs are also prescribed for adults and children with rheumatoid arthritis who fail to get relief from salicylates (such as aspirin) or other nonsteroidal anti-inflammatory drugs (such as ibuprofen).
Where can I order Sulfasalazine from? Can I buy Sulfasalazine at Canadian Prices?
Yes, if you are from the U.S. then you can buy Sulfasalazine at Canadian prices. Currently we will only accept an order for Sulfasalazine from U.S. and Canadian residents. Both U.S. and Canadian residents require a prescription to purchase Sulfasalazine and when you order Sulfasalazine it will be delivered with express shipping.
Most important fact about Sulfasalazine
Although ulcerative colitis rarely disappears completely, the risk of recurrence can be substantially reduced by the continued use of this drug.
How should you take Sulfasalazine?
Take Sulfasalazine in evenly spaced, equal doses, as determined by your doctor, preferably after meals or with food to avoid stomach upset. Swallow Sulfasalazine EN-tabs whole. It is important that you drink plenty of fluids while taking this medication to avoid kidney stones. If you are taking Sulfasalazine EN-tabs for rheumatoid arthritis, it may take up to 12 weeks for relief to occur. --If you miss a dose...Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once. --Storage instructions...
Store Sulfasalazine at room temperature.
What Sulfasalazine side effects may occur?
Sulfasalazine Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Sulfasalazine.
More common Sulfasalazine side effects may include:
Abdominal pain, anemia, bluish skin, fever, headache, hives, inflammation of the mouth, itching, lack of appetite, nausea, rash, stomach distress, vomiting
Less common or rare Sulfasalazine side effects may include:
Blood disorders, blood in the urine, bloody diarrhea, convulsions, diarrhea, diminished urination, drowsiness, hallucinations, hearing loss, hepatitis, inability to fall or stay asleep, intestinal inflammation, itchy skin eruptions, joint pain, kidney disorders, lack of muscle coordination, loss of hair, mental depression, red, raised rash, ringing in the ears, sensitivity to light, severe allergic reaction, skin discoloration, skin disorders, spinal cord defects, swelling around the eye, urinary tract infections, urine discoloration, vertigo
Possible food and drug interactions when taking Sulfasalazine
If Sulfasalazine is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Sulfasalazine with the following:
Digoxin (Lanoxin)
Folic acid (a B-complex vitamin)
Methotrexate (Rheumatrex)
Special information if you are pregnant or breastfeeding
The effects of Sulfasalazine during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Sulfasalazine is secreted in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.
Recommended Sulfasalazine dosage
Your doctor will carefully individualize your dosage and monitor your response periodically.
ULCERATIVE COLITIS
Adults The usual recommended initial dose of Sulfasalazine and Sulfasalazine EN-tabs is 3 to 4 grams daily divided into smaller doses (intervals between nighttime doses should not exceed 8 hours). In some cases the initial dosage is set at 1 to 2 grams daily to lessen side effects. As therapy continues, the dose is usually reduced to 2 grams daily. Children Aged 6 and Older The usual recommended initial dose is 40 to 60 milligrams per 2.2 pounds of body weight in each 24-hour period, divided into 3 to 6 doses. For the longer term, the dose is usually reduced to 30 milligrams per 2.2 pounds of body weight in each 24-hour period, divided into 4 doses. RHEUMATOID ARTHRITIS Adults The usual dose of Sulfasalazine EN-tabs is 2 grams a day, divided into smaller doses. Your doctor may have you start with a lower dose, then raise the dosage to 3 grams after 12 weeks. Children aged 6 and older
The typical recommended daily dosage is 30 to 50 milligrams per 2.2 pounds of body weight, up to a maximum of 2 grams, taken in 2 equally divided doses. To reduce the chance of digestive side effects and other reactions, the doctor will probably start with a fraction of the typical dose and build up to it over a period of weeks.
Sulfasalazine Overdosage
Any medication taken in excess can have serious consequences. If you suspect an Sulfasalazine overdose, seek emergency medical attention immediately.
Symptoms of Sulfasalazine overdose may include:
Abdominal pain, convulsions, drowsiness, nausea, stomach upset, vomiting
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