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Acticoat Burn Dressing Antimicrobial Barrier Dressing is an effective barrier to bacterial penetration. The barrier function of the dressing may help reduce infection in partial and full-thickness wounds including decubitus ulcers, venous stasis ulcers, diabetic ulcers, first- and second-degree burns, and donor sites. Acticoat* dressings may be used over debrided and grafted partial thickness wounds. The silver antimicrobial barrier dressing consists of a rayon/polyester non-woven core laminated (by sonic welds) between an upper and lower layer of silver coated high density polyethylene mesh (HDPE). The laminations are held in place with ultrasound welds. The silver coated HDPE layers are designed to be barriers against microbial infection of a wound. Rayon/polyester core helps manage moisture level and control silver release. Silver-coated high-density polyethylene mesh facilitates the passage of silver through the dressing. The nanocrystalline coating of pure silver delivers antimicrobial barrier activity within 30 minutes - faster than other forms of silver. NUCRYST Pharmaceutical's antimicrobial technology is able to produce silver-coated polyethylene films that can release an effective concentration of silver over several days. Thus, as silver ions are consumed, additional silver is released from the dressing to provide an effective antimicrobial barrier. This patented silver-based antimicrobial technology can be applied to a wide range of medical devices including wound dressings, certain types of catheters and various implants to prevent infection. This technology was first applied to burn wound dressings because burns present a very severe risk of infection.
Acticoat
Acticoat with SILCRYST™ Nanocrystals is an effective antimicrobial barrier dressing. The nanocrystalline coating of silver rapidly kills a broad spectrum of bacteria in as little as 30 minutes and is effective for at least 3 days¹. Acticoat dressing consists of three layers: an absorbent inner core sandwiched between outer layers of silver coated, low adherent polyethylene net. Nanocrystalline silver protects the wound site from bacterial contamination while the inner core helps maintain the moist environment optimal for wound healing.
Acticoat and Acticoat 7 can be used in chronic and burn wound management as an antimicrobial barrier layer over partial and full thickness wounds.
Acticoat consists of two layers of a silver-coated, high-density polyethylene mesh, enclosing a single layer of an apertured non-woven fabric of rayon and polyester. The three components are ultrasonically welded together to maintain the integrity of the dressing in use. Silver is applied to the polyethylene mesh by a vapour deposition process, which results in the formation of microscopic `nanocrystals' of metallic silver.
In this nanocrystalline form, metallic silver exhibits pronounced antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria including strains resistant to many types of antibiotics. It is also effective against clinically important strains of yeasts and fungi.
Acticoat Indications
Acticoat is used as an antimicrobial barrier layer for partial and full-thickness wounds such as burns, donor sites and graft recipient sites that are judged to be at risk from infection.
Acticoat Contra-indications
Acticoat is contra-indicated in patients with known hypersensitivity to any of the components of the product. If signs of a sensitivity reaction develop during use, treatment should be discontinued. No safety issues associated with the use of Acticoat have been identified to date.
Acticoat Method of use
It is recommended that prior to use Acticoat be moistened with sterile water, not saline. This will help to ensure that the dressing provides a moist wound-healing environment whilst enabling the silver to exert its antimicrobial effect.
If necessary, the dressing may be trimmed to the appropriate size and shape of the wound prior to application taking care that the darker blue surface is placed in direct contact with the skin.
Acticoat should be covered with a secondary dressing the choice of which is determined by the degree of exudate produced by the wound and held in place with surgical tape or a bandage as appropriate.
Acticoat Frequency of Change
It is recommended that the dressing be left in place for a maximum of three days, although on very heavily exuding wounds, it may be necessary to replace it more frequently.
Acticoat Warnings
Acticoat should not be used with oil-based products or other topical antimicrobials.
If applied to very lightly exuding wounds there is a possibility that the dressing may dry out and adhere to the wound surface. This is more likely to happen if the secondary dressing is very absorbent or highly permeable to water vapour.
If adherence becomes a problem the dressing should be soaked off to avoid causing pain or trauma to the underlying tissue.
Acticoat Presentation
Acticoat is presented in laminated peel pouch, sealed with a laminated cover and sterilised by gamma irradiation.
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