FORTOVASE DESCRIPTION

Fortovase (saquinavir) - Also known as Invirase

Why is Fortovase prescribed?

Fortovase is used in the treatment of advanced human immunodeficiency virus (HIV) infection. HIV causes the immune system to break down so that it can no longer fight off other infections. This leads to the fatal disease known as acquired immune deficiency syndrome (AIDS).

Fortovase belongs to a class of HIV drugs called protease inhibitors, which work by interfering with an important step in the virus's reproductive cycle. Fortovase is used in combination with other HIV drugs called nucleoside analogues (Retrovir or Hivid, for example). The combination produces an increase in the immune system's vital CD4 cells (white blood cells) and reduces the amount of virus in the bloodstream.

Where can I order Fortovase From? Can I buy Fortovase at Canadian Prices?

Yes, if you are from the U.S. then you can buy Fortovase at Canadian prices. Currently we will only accept an order for Fortovase from U.S. and Canadian residents. Both U.S. and Canadian residents require a prescription to purchase Fortovase and when you order Fortovase it will be delivered with express shipping.

Most important fact about Fortovase

Fortovase will not cure an HIV infection. You will continue to face the possibility of complications, including opportunistic infections (rare infections that develop only when the immune system falters, such as certain types of pneumonia, tuberculosis, and fungal infections). Therefore, it is important that you remain under the care of a doctor and keep all your follow-up appointments.

How should you take Fortovase?

Take this medication exactly as prescribed by your doctor. Do not share this medication with anyone and do not exceed your recommended dosage. Take Fortovase with a meal or within 2 hours afterwards. This allows the drug to be properly absorbed by your body. Your doctor will perform laboratory tests before you start therapy with Fortovase and at regular intervals during your therapy to see how you are reacting to the medication.

--If you miss a dose...

Take it as soon as possible. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take a double dose.

--Storage instructions...

Store Fortovase in the refrigerator in a tightly closed bottle. The capsules should be used within 3 months if they've been allowed to reach room temperature.

What Fortovase side effects may occur?

Fortovase Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Fortovase.

Possible Fortovase side effects may include:
Abdominal discomfort and pain, appetite disturbance, depression, diarrhea, dizziness, fatigue, gas, headache, indigestion, mouth sores, muscle and bone pain, nausea, numbness in the arms and legs, tingling or "pins and needles" sensation, vomiting, weakness

Possible food and drug interactions when taking Fortovase

Protease inhibitors such as Fortovase tend to raise blood levels of the cholesterol drugs known as "statins," increasing the chance of dangerous side effects. Do not combine Fortovase with Mevacor or Zocor. Be cautious when combining it with Lipitor.

If Fortovase is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Fortovase with the following:

Carbamazepine (Tegretol)
Certain migraine drugs, including D.H.E. 45 injection, Cafergot, Ergostat, and Migranal Nasal Spray
Clarithromycin (Biaxin)
Delavirdine (Rescriptor)
Dexamethasone (Decadron)
Indinavir (Crixivan)
Ketoconazole (Nizoral)
Midazolam (Versed)
Nelfinavir (Viracept)
Nevirapine (Viramune)
Phenobarbital (Donnatal)
Phenytoin (Dilantin)
Rifabutin (Mycobutin)
Rifampin (Rifadin)
Ritonavir (Norvir)
Sildenafil (Viagra)
St. John's wort
Triazolam (Halcion)

Be sure to tell your doctor and pharmacist about all the medications (both prescription and over-the-counter) that you are presently taking. Alert them, too, whenever you stop taking a medication.

Special Fortovase information if you are pregnant or breastfeeding

The effects of Fortovase during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, tell your doctor immediately. Do not breastfeed. HIV appears in breast milk and can be passed to a nursing infant.

Recommended Fortovase dosage

ADULTS

The recommended dosage is 1200 milligrams (six 200-milligram capsules), taken 3 times a day with a meal or within 2 hours afterwards. Daily doses lower than 1200 milligrams 3 times a day are not recommended, since they will not have the same antiviral activity. You should also be taking Retrovir, Hivid, or another antiviral drug as directed.

CHILDREN

The safety and effectiveness of Fortovase in children younger than 16 years of age have not been established.

Fortovase Overdosage

There have been no reports of Fortovase poisoning. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek emergency medical treatment immediately.

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