Myleran is an antineoplastic used to treat certain cancers.
Why is Myleran prescribed?
Myleran, an anticancer drug, works by interfering with the growth of malignant cells. It may be used alone but is often given with other anticancer medications. Myleran is used in the treatment of the following types of cancer:
Breast cancer
Leukemias (cancers affecting the white blood cells)
Malignant lymphomas (Hodgkin's disease or cancer of the lymph nodes)
Multiple myeloma (a malignant condition or cancer of the plasma cells)
Advanced mycosis fungoides (cancer of the skin and lymph nodes)
Neuroblastoma (a malignant tumor of the adrenal gland or sympathetic nervous system)
Ovarian cancer (adenocarcinoma)
Retinoblastoma (a malignant tumor of the retina)
In addition, Myleran may sometimes be given to children who have "minimal change" nephrotic syndrome (kidney damage resulting in loss of protein in the urine) and who have not responded well to treatment with steroid medications.
Where can I order Myleran from? Can I buy Myleran at Canadian Prices?
Yes, if you are from the U.S. then you can buy Myleran at Canadian prices. Currently we will only accept an order for Myleran from U.S. and Canadian residents. Both U.S. and Canadian residents require a prescription to purchase Myleran and when you order Myleran it will be delivered with express shipping.
Most important fact about Myleran
Myleran may cause bladder damage, probably from toxic byproducts of the drug that are excreted in the urine. Potential problems include bladder infection with bleeding and fibrosis of the bladder.
While you are being treated with Myleran, drink 3 or 4 liters of fluid a day to help prevent bladder problems. The extra fluid will dilute your urine and make you urinate frequently, thus minimizing the Myleran byproducts' contact with your bladder.
How should you take Myleran?
Take Myleran exactly as prescribed. You will undergo frequent blood tests, and the doctor will adjust your dosage depending on your white blood cell count; a dosage reduction is necessary if the count drops below a certain level. You will also have frequent urine tests to check for blood in the urine, a sign of bladder damage. Take Myleran on an empty stomach. If you have severe stomach upset, then you may take it with food. If you are unable to swallow the tablet form, you may be given an oral solution made from the injectable form of Myleran and Aromatic Elixir. This solution should be used within 14 days. ---If you miss a dose...Do not take the dose you missed. Go back to your regular schedule and contact your doctor. Do not take 2 doses at once. ---Storage instructions...
Store tablets at room temperature. Store the oral solution in the refrigerator.
What side effects may occur with Myleran?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor immediately. Only your doctor can determine if it is safe for you to continue using Myleran. One possible Myleran side effect is the development of a secondary cancer, typically of the bladder, lymph nodes, or bone marrow. A secondary cancer may occur up to several years after the drug is given. Myleran can lower the activity of your immune system, making you more vulnerable to infection. Noncancerous bladder problems may occur during Myleran therapy (see "Most important fact about this drug" section, above).
More common side effects may include:
Loss of appetite, nausea and vomiting, temporary hair loss
Less common or rare side effects may include:
Abdominal pain, anemia, bleeding, darkening of the skin and changes in fingernails, decreased sperm count, diarrhea, fever, infections, infertility, lung infections, missedmenstrual periods, mouth sores, new tumor growth, other cancers, rash, severe allergic reaction, slow wound healing, yellowing of eyes and skin
Possible food and drug interactions when taking Myleran
If Myleran is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Myleran with the following:
Anticancer drugs such as Adriamycin
Allopurinol (the gout medicine Zyloprim)
Phenobarbital
If you take adrenal steroid hormones because you have had your adrenal glands removed, you are at increased risk for toxic effects from Myleran; your dosage of both the steroids and Myleran may need to be modified.
Special information if you are pregnant or breastfeeding while taking Myleran
If you are pregnant or plan to become pregnant, inform your doctor immediately. When taken during pregnancy, Myleran can cause defects in the unborn baby. Women taking Myleran should use effective contraception. Myleran does appear in breast milk. A new mother will need to choose between taking this drug and nursing her baby.
Recommended Myleran dosage
ADULTS AND CHILDREN
Malignant Diseases
Your doctor will tailor your dosage according to your condition and other drugs taken with Myleran. The recommended oral dosage range is 1 to 5 milligrams per 2.2 pounds of body weight per day.
CHILDREN
"Minimal Change" Nephrotic Syndrome
The recommended oral dosage is 2.5 to 3 milligrams per 2.2 pounds of body weight per day for a period of 60 to 90 days.
Myleran Overdosage
Although there is no specific information on Myleran overdose, any medication taken in excess can have serious consequences. If you suspect an overdose of Myleran, seek medical attention immediately.
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