Manufactured by Janssen Pharmaceutical. Sporanox is used to treat certain types of fungal infections, both internally (inside the body) and externally (skin and nails). It works by preventing the fungus from growing. If you use the PulsePak, you will take SPORANOX for 1 week and then take no SPORANOX for the next 3 weeks before repeating the 1-week treatment. This is called "pulse dosing." The SPORANOX PulsePak contains enough medicine for one "pulse" (1 week of treatment). The SPORANOX PulsePak comes with special instructions. It contains 7 pouches - one for each day of treatment. Inside each pouch is a card containing 4 capsules. Looking at the back of the card, fold it back along the dashed line and peel away the backing so that you can remove 2 capsules.
Why is Sporanox prescribed?
Sporanox capsules are used to treat four types of serious fungal infection: blastomycosis, histoplasmosis, aspergillosis, and onychomycosis. Blastomycosis can affect the lungs, bones, and skin. Histoplasmosis can affect the lungs, heart, and blood. Aspergillosis can affect the lungs, kidneys, and other organs. Onychomycosis affects the nails. Sporanox is also used against fungal infections in people with weak immune systems, such as AIDS patients.
Sporanox oral solution is used to treat candidiasis (fungal infection) of the mouth, throat, and gullet (esophagus), and for other fungal infections in people with weakened immunity and fever.
How should you take Sporanox?
Take Sporanox exactly as prescribed. To make sure the capsules are properly absorbed, you should take them after a full meal; the oral solution should be taken without food. A cola drink can help some people absorb the capsules better. Continue taking Sporanox until all the medication is gone. Do not take antacids within 1 hour before or 2 hours after taking Sporanox.
Swish the oral solution, 10 milliliters at a time, in your mouth for a few seconds before swallowing it. Mouth and throat candidiasis should clear up in several days. The oral solution and capsules cannot be used interchangeably. --If you miss a dose...Take the forgotten dose as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule. Never try to ``catch up'' by doubling the dose. --Storage instructions...
Store Sporanox at room temperature. Protect the capsules from light and moisture. Do not freeze the oral solution.
What Sporanox side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Sporanox.
More common Sporanox side effects may include:
Anxiety, bursitis, diarrhea, fatigue, fever, gas, headache, high blood pressure, indigestion, injury, muscle pain, nasal and sinus inflammation, nausea, pain, rash, respiratory infection, swelling due to water retention, urinary infection, vomiting
Less common Sporanox side effects may include:
Abdominal pain, abnormal dreams, allergic reaction, decreased sexual drive, dizziness, extreme sleepiness, feeling of general discomfort, gum inflammation, hives, increased appetite, inflamed stomach and intestines, itching, loss of appetite, reproductive disorders such as male impotence, sleepiness, sore throat, tremor, weakness
Rare Sporanox side effects may include:
Blood abnormalities, congestive heart failure, constipation, depression, fluid in the lungs, hair loss, hepatitis, high triglyceride levels, liver failure, male breast development, male breast pain, menstrual disorders, nerve disorders, ringing in the ears, severe allergic reaction, skin peeling, sleeplessness
Additional Sporanox side effects that may be seen with the oral solution are:
Back pain, blood in the urine, breathing difficulty, chest pain, cough, dehydration, difficulty swallowing, hemorrhoids, hot flushes, impaired speech, inflamed mouth, insomnia, pneumonia, shivering, sweating, vision problems, weight loss
People being treated for onychomycosis may experience stomach and intestinal disorders or rash, or, less commonly, headache, light-headedness upon standing up, low blood pressure, muscle pain, a sick feeling, or vertigo.
Special Sporanox information if you are pregnant or breastfeeding
The effects of Sporanox during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. You should not take Sporanox to treat onychomycosis if you are or may become pregnant. In any event, Sporanox should not be used during pregnancy if the problem is a nail infection. In other cases, check with your doctor before you take Sporanox.
Sporanox appears in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Sporanox is finished.
Recommended Sporanox dosage
ADULTS Blastomycosis and Histoplasmosis
The usual dose is two 100-milligram capsules, taken after a full meal once a day. If you feel no improvement, or if there is evidence that the fungal disease has spread, your doctor will increase the dose 100 milligrams at a time to a maximum of 400 milligrams a day. Daily dosages above 200 milligrams a day should be divided into 2 smaller doses. Aspergillosis The usual dose is 200 to 400 milligrams a day. Treatment usually continues for a minimum of 3 months, until tests indicate that the fungal infection has subsided. Onychomycosis The usual dose for a toenail infection, whether or not fingernails are also involved, is 200 milligrams once a day for 12 weeks. If only fingernails are infected, treatment is given in two 7-day-long sessions during which you take 200 milligrams of Sporanox twice a day, with a 3-week rest period between sessions. Candidiasis, mouth and throat The usual dose is 20 milliliters of oral solution a day for 1 to 2 weeks. If the infection does not go away, your dose will be changed to 10 milliliters twice a day. Candidiasis, esophagus The usual dose is 10 milliliters of oral solution a day for at least 3 weeks. You should continue the treatment for 2 weeks after your symptoms clear up. If necessary, the doctor may increase the dose to 20 milliliters a day. Fungal infections in people with weakened immunity and fever Recommended treatment starts with 200-milligram injections twice a day for 2 days followed by 200 milligrams injected once a day for up to 14 days. This may be followed by 20 milliliters of oral solution twice a day for up to a total of 28 days of treatment
CHILDREN The safety and effectiveness of Sporanox in children have not been established.
Sporanox Overdosage
Any drug taken in excess can have dangerous consequences. If you suspect an overdose, seek emergency medical treatment immediately.
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