ACCUPRIL DESCRIPTION
Accupril
Accupril is manufactured by Pfizer. Accupril TABLETS CAN be split in half. This medicine is an ACE inhibitor used to treat high blood pressure. It may also be used to treat congestive heart disease and other conditions as determined by your doctor.
Quinapril hydrochloride is the hydrochloride salt of quinapril, the ethyl ester of a nonsulfhydryl, angiotensin-converting enzyme (ACE) inhibitor, quinaprilat.
Quinapril hydrochloride is chemically described as (3S-(2(R*(R*)), 3R*))-2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3, 4-tetrahydro-3-isoquinolinecarboxylic acid, monohydrochloride. Its empirical formula is C25H30N2O5·HCl.
Quinapril hydrochloride is a white to off-white amorphous powder that is freely soluble in aqueous solvents.
Accupril tablets contain 5 mg, 10 mg, 20 mg, or 40 mg of quinapril for oral administration. Each tablet also contains candelilla wax, crospovidone, gelatin, lactose, magnesium carbonate, magnesium stearate, synthetic red iron oxide, and titanium dioxide.
Brand name:
Where can I order Accupril from? Can I buy Accupril at Canadian prices?
Yes, if you are from the U.S. then you can buy Accupril at Canadian prices. Currently we will only accept an order for Accupril from U.S. and Canadian residents. Both U.S. and Canadian residents require a prescription to purchase Accupril and when you order Accupril it will be shipped with express shipping.
Accupril
Pronounced: AK-you-prill
Generic name: Quinapril hydrochloride
Why is accupril prescribed?
Accupril is used in the treatment of high blood pressure. It can be taken alone or in combination with a thiazide type of water pill such as HydroDIURIL. Accupril is in a family of drugs known as "ACE inhibitors." It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form that increases salt and water retention in your body. Accupril also enhances blood flow throughout your blood vessels. Along with other drugs, Accupril is also prescribed in the treatment of congestive heart failure.
Most important fact about Accupril
You must take Accupril regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Accupril; and you must continue taking it even if you are feeling well. Accupril does not cure high blood pressure; it merely keeps it under control.
How should you take Accupril?
You can take Accupril with or without meals. Alcohol may increase the effect of Accupril, and could cause dizziness or fainting. Avoid alcoholic beverages until you have checked with your doctor. Take Accupril exactly as prescribed, and see your doctor regularly to make sure the drug is working properly without unwanted side effects. Do not stop taking this drug without first consulting your doctor. --If you miss a dose...Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never try to "catch up" by doubling the dose. --Storage instructions...
Accupril can be stored at room temperature. Protect from light.
What Accupril side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Accupril.
More common side effects may include:
Dizziness, headache
Less common Accupril side effects may include:
Abdominal pain, coughing, fatigue, nausea, vomiting
Rare Accupril side effects may include:
Angina (severe chest pain), back pain, bleeding in the stomach or intestines, bronchitis, changes in heart rhythm, constipation, depression, diarrhea, dimmed vision, dizziness when first standing up, dry mouth or throat, extremely high blood pressure, fainting, fluid accumulation and swelling, gas, hair loss, heart attack, heart failure, hepatitis, high potassium, impotence, increased blood pressure, increased sweating, indigestion, inflammation of the pancreas, inflammation of the sinuses, insomnia, itching, kidney failure, joint pain, low blood pressure, muscle pain, nervousness, numbness/tingling, palpitations, rapid heartbeat, rash, sensitivity to light, severe allergic reactions, skin peeling, sleepiness, sore throat, stroke, swelling of the mouth and throat, urinary tract infection, vague feeling of illness, vertigo
Why should this drug not be prescribed?
If you are sensitive to or have ever had an allergic reaction to Accupril or similar drugs, such as Capoten and Vasotec, you should not take this medication. Make sure your doctor is aware of any drug reactions you have experienced.
Special warnings about this medication
If you develop swelling of the face, lips, tongue, or throat, or of your arms and legs, or have difficulty swallowing or breathing, you should contact your doctor immediately. You may need emergency treatment.
You may feel light-headed, especially during the first few days of Accupril therapy. If this occurs, notify your doctor. If you actually faint, stop taking the medication until you have consulted with your doctor.
Vomiting, diarrhea, and heavy perspiration can all deplete your body fluid; and dehydration can cause your blood pressure to drop. If this leads to light-headedness or fainting, you should check with your doctor.
Inform your doctor or dentist that you are taking Accupril before undergoing surgery or anesthesia.
Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor.
If you develop a sore throat, fever, or any other sign of infection, contact your doctor immediately. It could indicate a more serious illness.
If you are taking Accupril, your doctor will do a complete assessment of your kidney function and will watch it closely as long as you are taking this drug.
If you notice a yellow tinge to your skin and the whites of your eyes, stop taking the drug and notify your doctor immediately. This could be a sign of liver damage.
The safety and effectiveness of Accupril in children have not been established.
Possible food and drug interactions when taking this medication
If Accupril is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Accupril with the following:
Diuretics such as Lasix
Lithium (Eskalith, Lithobid)
Magnesium
Potassium-sparing diuretics such as Aldactone, Dyazide, and Moduretic
Potassium supplements such as Slow-K and K-Dur
Salt substitutes containing potassium
Tetracycline (Sumycin)
Special information if you are pregnant or breastfeeding
ACE inhibitors such as Accupril have been shown to cause injury and even death to the unborn child when used in pregnancy during the second and third trimesters. If you are pregnant, your doctor should discontinue Accupril as soon as possible. If you plan to become pregnant, make sure your doctor knows you are taking this medication. Accupril appears in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.
Recommended Accupril dosage
HIGH BLOOD PRESSURE
The usual starting dose is 10 or 20 milligrams taken once a day. If you have any problems with your kidneys or if you are also taking a diuretic, your starting dose may be lower. For adults over age 65, the usual starting dose is 10 milligrams. Depending on how your blood pressure responds, your doctor may increase your dose up to a total of 80 milligrams a day taken once a day or divided into two doses.
CONGESTIVE HEART FAILURE
The usual starting dose is 5 milligrams taken twice a day. Your doctor may increase the dose from week to week, up to as much as 20 to 40 milligrams daily, divided into 2 equal doses. If you have kidney problems, the dosage will be lower.
Accupril Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.
A severe drop in blood pressure is the primary sign of an Accupril overdose.
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