Pentasa is an anti-inflammatory used to treat ulcerative colitis. It may also be used for other conditions as determined by your doctor.
Brand Name
Pentasa
Common Name
5-aminosalicylic acid enteric coated
Where can I order Pentasa from? Can I buy Pentasa at Canadian Prices?
Yes, if you are from the U.S. then you can buy Pentasa at Canadian prices. Currently we will only accept an order for Pentasa from U.S. and Canadian residents. Both U.S. and Canadian residents require a prescription to purchase Pentasa and when you order Pentasa it will be delivered with express shipping.
How does Pentasa work? What will it do for me?
Pentasa may be used to treat ulcerative colitis and Crohn's disease, which are types of inflammatory bowel disease. It is used for mild and moderate cases of these diseases. It acts by reducing inflammation in the bowel.
Different brands of 5-aminosalicylic acid are designed to act on different places in the gastrointestinal tract (the "digestion tube" that runs from the mouth to the anus). Ulcerative colitis affects the colon and rectum only, while Crohn's disease affects the whole gastrointestinal tract. For this reason, some brands are used to treat only ulcerative colitis, while others can be used to treat both Crohn's disease and ulcerative colitis.
Your doctor may choose to use Pentasa for other conditions not listed here. If you're unsure why you are taking Pentasa, contact your doctor.
How should I use Pentasa?
Tablet: The recommended adult dose of tablets ranges between 1.5 g and 4 g daily taken in divided doses depending on the product selected. Swallow the tablets whole, ensuring that you do not break the outer coating. Take the tablets only as prescribed. Do not change the number or frequency of tablets ingested without first consulting your doctor.
Suppository, rectal suspension, enema: The usual dose for suppositories, rectal suspension, and enema is 1 g to 4 g daily divided into one or two doses, or as prescribed by the doctor.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is very important that Pentasa be taken regularly, exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue on with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue on with your regular dosing schedule. Do not double doses.
What form(s) does Pentasa come in?
Tablet
Who should NOT take Pentasa?
Pentasa should not be used by anyone who:
has a history of allergy to Pentasa or other salicylates (e.g., ASA)
has a gastric or duodenal ulcer
has a urinary tract obstruction
is under 2 years of age
What side effects are possible with Pentasa?
The side effects listed below are not experienced by everyone who takes Pentasa. If you are concerned about side effects, discuss the risks and benefits of Pentasa with your doctor. Your health professional may be able to help you deal with some of the effects.
The following side effects may go away as your body becomes used to the medication; check with your doctor if they continue or become bothersome.
More common:
abdominal or stomach cramps or pain (mild)
dizziness
headache (mild)
diarrhea (mild)
runny or stuffy nose or sneezing
Less common:
acne
back or joint pain
gas
heartburn or indigestion
loss of appetite
loss of hair
Stop taking Pentasa and check with your doctor immediately if any of the following side effects occur:
Less common:
abdominal or stomach cramps or pain (severe)
bloody diarrhea
fever
skin rash and itching
Rare:
anxiety
severe back or stomach pain
blue or pale skin
signs of heart attack (e.g., chest pain, possibly moving to the left arm, neck, or shoulder)
chills
fast heartbeat
nausea or vomiting
shortness of breath
swelling of the stomach
unusual tiredness of weakness
yellow eyes or skin
Other side effects not listed above may occur in some people. Check with your doctor if you notice any symptom that worries you while you are taking Pentasa.
Are there any other precautions or warnings for Pentasa?
Reduced kidney or liver function: People with reduced kidney or liver function should exercise caution in taking Pentasa.
Tablets in stool: Infrequently, what look to be intact or partially intact tablets may appear in the stool. If this occurs repeatedly, consult your doctor.
Slow emptying of stomach: Pentasa may not work as well for people with a condition known as pyloric stenosis.
Pregnancy: Pentasa should be used during pregnancy only if clearly needed. If you are or may be pregnant, talk to your doctor.
Breast-feeding: If you are breast-feeding, talk to your doctor about the risks and benefits of using Pentasa.
Children: The safety and effectiveness of 5-ASA for use by children have not been established.
What other drugs could interact with Pentasa?
The following medications may affect how 5-aminosalicylic acid works or increase the risk of side effects:
lactulose
sulfonylureas (e.g., glyburide, gliclazide)
If you are taking any medications containing this drug, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
stop taking one of the medications,
change one of the medications to another,
change how you are taking one or both of the medications, or
leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Pentasa. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription) and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or illegal drugs can affect the action of many medications, you should let your prescriber know if you use them.
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