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                   This medicine is an antibiotic used to treat or prevent infections. 
                    
                  Brand Name 
                  Proloprim 
                  Common Name 
                  trimethoprim
  
                  Where can I order Proloprim from? Can I buy Proloprim at Canadian Prices? 
                  Yes, if you are from the U.S. then you can buy Proloprim at Canadian prices. Currently we will only accept an order for Proloprim from U.S. and Canadian residents. Both U.S. and Canadian residents require a prescription to purchase Proloprim and when you order Proloprim it will be delivered with express shipping. 
                  How does Proloprim work? What will it do for me? 
                  Proloprim belongs to the class of medications called antibiotics. It is used for the treatment of certain types of infections caused by bacteria. It is most commonly used to treat bladder (urinary tract) infections. Proloprim works by killing the bacteria that cause the infection. 
                  Your doctor may have suggested Proloprim for conditions other than the ones listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Proloprim, speak to your doctor. Do not stop taking Proloprim without consulting your doctor. 
                  How should I use Proloprim? 
                  The recommended adult dose of Proloprim is 100 mg twice daily (every 12 hours) or 200 mg once daily (every 24 hours) for a period of 10 days. Proloprim may be taken with or without meals. 
                  Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor. 
                  It is very important that Proloprim be taken exactly as prescribed by your doctor. Finish all of Proloprim, even if you start to feel better. If you miss a dose, take it as soon as possible and continue on with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue on with your regular dosing schedule. Do not double doses. 
                  Who should NOT take Proloprim? 
                  Proloprim should not be used by anyone who: 
                  is allergic to Proloprim or any of the other ingredients of the medication 
                  has a blood condition known as megaloblastic anemia (caused by folate deficiency) 
                  is pregnant 
                  is breast-feeding 
                  What side effects are possible with Proloprim? 
                  The side effects listed below are not experienced by everyone who takes Proloprim. If you are concerned about side effects, discuss the risks and benefits of Proloprim with your doctor. Your health professional may be able to help you deal with some of the effects. 
                  The following side effects may go away as your body becomes used to the medicine; check with your doctor if they continue or become bothersome. 
                  Less common: 
                  diarrhea 
                  loss of appetite 
                  nausea or vomiting 
                  stomach cramps or pain 
                  Check with your doctor immediately if any of the following side effects occur: 
                  Less common: 
                  skin rash or itching 
                  Rare: 
                  black, tarry stools 
                  blood in urine or stools 
                  bluish fingernails, lips, or skin 
                  changes in facial skin colour 
                  chills 
                  difficulty breathing or shortness of breath 
                  fever, with or without chills 
                  general feeling of discomfort or illness 
                  headache 
                  joint or muscle pain 
                  nausea 
                  neck stiffness 
                  pale skin 
                  pinpoint-sized red spots on skin 
                  redness, blistering, burning, tenderness, peeling, or loosening of skin or mucous membranes 
                  redness, swelling, or soreness of tongue 
                  red skin lesions, often with a purple center 
                  sore throat 
                  swelling 
                  thickened or scaly skin 
                  unusual bleeding or bruising 
                  unusual tiredness or weakness
  
                  Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Proloprim. 
                  Are there any other precautions or warnings for Proloprim? 
                  Blood disorders: The presence of sore throat, fever, pale skin, rash, or jaundice (yellowing of the skin) may be early signs of rare but serious blood disorders. Anyone who develops these symptoms after starting Proloprim should contact their doctor. 
                  Folic acid levels: Proloprim should be taken with caution by anyone with a possible folic acid deficiency. 
                  Kidney and liver function: Proloprim should be taken with caution by anyone with reduced kidney or liver function. 
                  Skin rash: If the recommended dosage is doubled, skin rashes are more likely to occur. 
                  Pregnancy and breast-feeding: Proloprim should not be taken by pregnant or breast-feeding women. 
                  Children: The safety of Proloprim for infants younger than two months of age has not been established. The effectiveness of Proloprim alone (i.e., not in combination with other antibiotics) has not been established for children younger than 12 years of age.
  
                  What other drugs could interact with Proloprim? 
                  The following may affect how Proloprim works or increase the risk of side effects: 
                  alcohol 
                  dapsone 
                  methotrexate 
                  Proloprim may affect how the following medications work: 
                  dapsone 
                  phenytoin 
                  procainamide 
                  If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to: 
                  stop taking one of the medications, 
                  change one of the medications to another, 
                  change how you are taking one or both of the medications, or 
                  leave everything as is. 
                  An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed. 
                  Medications other than those listed above may interact with Proloprim. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. 
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