Efavirenz Side Effects

When dealing with Efavirenz side effects, the unwanted reactions that can occur while taking the antiretroviral drug Efavirenz. Also known as Efavirenz adverse reactions, they often show up as neurological, dermatological, or metabolic issues and can influence how well a patient sticks to HIV therapy.

Efavirenz itself is a non‑nucleoside reverse transcriptase inhibitor (NNRTI), a key component of many antiretroviral therapy (ART) regimens used to suppress HIV replication. Because ART relies on consistent drug levels, drug interactions, facts like CYP2B6 metabolism and co‑administered medicines, can amplify or mute Efavirenz’s effects. One of the most common clusters of side effects involves the central nervous system (CNS). Patients often report vivid dreams, dizziness, or mood changes, which are categorized as CNS side effects, symptoms that stem from the drug’s impact on brain chemistry. These CNS reactions can be especially troubling for people starting treatment, but they usually lessen after a few weeks as the body adjusts. Skin reactions, ranging from mild rashes to severe Stevens‑Johnson syndrome, form another important subgroup. Metabolic changes, such as altered lipid profiles or liver enzyme elevations, add a layer of complexity for clinicians monitoring long‑term health.

Understanding how Efavirenz side effects fit into the broader picture of HIV care helps patients and providers make smarter choices. You’ll see discussions on managing CNS symptoms with dose timing, using antihistamines for rash relief, and checking liver function before and during therapy. The articles below break down each side‑effect category, compare Efavirenz with newer NNRTIs, and offer practical steps to reduce discomfort while staying on track with ART. Armed with this knowledge, you can spot early warning signs, talk confidently with your healthcare team, and keep your treatment plan on the right track. Below you’ll find a curated selection of posts that dive deeper into these topics.