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Brand Name
Proloprim
Common Name
trimethoprim
Where can I order Trimethoprim from? Can I buy Trimethoprim at Canadian Prices?
Yes, if you are from the U.S. then you can buy Trimethoprim at Canadian prices. Currently we will only accept an order for Trimethoprim from U.S. and Canadian residents. Both U.S. and Canadian residents require a prescription to purchase Trimethoprim and when you order Trimethoprim it will be delivered with express shipping.
How does Trimethoprim work? What will it do for me?
Trimethoprim belongs to the class of medications called antibiotics. It is used for the treatment of certain types of infections caused by bacteria. It is most commonly used to treat bladder (urinary tract) infections. Trimethoprim works by killing the bacteria that cause the infection.
Your doctor may have suggested Trimethoprim for conditions other than the ones listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Trimethoprim, speak to your doctor. Do not stop taking Trimethoprim without consulting your doctor.
How should I use Trimethoprim?
The recommended adult dose of Trimethoprim is 100 mg twice daily (every 12 hours) or 200 mg once daily (every 24 hours) for a period of 10 days. Trimethoprim may be taken with or without meals.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is very important that Trimethoprim be taken exactly as prescribed by your doctor. Finish all of Trimethoprim, even if you start to feel better. If you miss a dose, take it as soon as possible and continue on with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue on with your regular dosing schedule. Do not double doses.
Who should NOT take Trimethoprim?
Trimethoprim should not be used by anyone who:
is allergic to Trimethoprim or any of the other ingredients of the medication
has a blood condition known as megaloblastic anemia (caused by folate deficiency)
is pregnant
is breast-feeding
What side effects are possible with Trimethoprim?
The side effects listed below are not experienced by everyone who takes Trimethoprim. If you are concerned about side effects, discuss the risks and benefits of Trimethoprim with your doctor. Your health professional may be able to help you deal with some of the effects.
The following side effects may go away as your body becomes used to the medicine; check with your doctor if they continue or become bothersome.
Less common:
diarrhea
loss of appetite
nausea or vomiting
stomach cramps or pain
Check with your doctor immediately if any of the following side effects occur:
Less common:
skin rash or itching
Rare:
black, tarry stools
blood in urine or stools
bluish fingernails, lips, or skin
changes in facial skin colour
chills
difficulty breathing or shortness of breath
fever, with or without chills
general feeling of discomfort or illness
headache
joint or muscle pain
nausea
neck stiffness
pale skin
pinpoint-sized red spots on skin
redness, blistering, burning, tenderness, peeling, or loosening of skin or mucous membranes
redness, swelling, or soreness of tongue
red skin lesions, often with a purple center
sore throat
swelling
thickened or scaly skin
unusual bleeding or bruising
unusual tiredness or weakness
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Trimethoprim.
Are there any other precautions or warnings for Trimethoprim?
Blood disorders: The presence of sore throat, fever, pale skin, rash, or jaundice (yellowing of the skin) may be early signs of rare but serious blood disorders. Anyone who develops these symptoms after starting Trimethoprim should contact their doctor.
Folic acid levels: Trimethoprim should be taken with caution by anyone with a possible folic acid deficiency.
Kidney and liver function: Trimethoprim should be taken with caution by anyone with reduced kidney or liver function.
Skin rash: If the recommended dosage is doubled, skin rashes are more likely to occur.
Pregnancy and breast-feeding: Trimethoprim should not be taken by pregnant or breast-feeding women.
Children: The safety of Trimethoprim for infants younger than two months of age has not been established. The effectiveness of Trimethoprim alone (i.e., not in combination with other antibiotics) has not been established for children younger than 12 years of age.
What other drugs could interact with Trimethoprim?
The following may affect how Trimethoprim works or increase the risk of side effects:
alcohol
dapsone
methotrexate
Trimethoprim may affect how the following medications work:
dapsone
phenytoin
procainamide
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
stop taking one of the medications,
change one of the medications to another,
change how you are taking one or both of the medications, or
leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Trimethoprim. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
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