Wellbutrin is an antidepressant used to treat depression. It may also be used to treat other conditions as determined by your doctor. This medicine is a TABLET but CANNOT be split.
Why is Wellbutrin prescribed?
Wellbutrin, a relatively new antidepressant medication, is given to help relieve certain kinds of major depression. Major depression involves a severely depressed mood (for 2 weeks or more) and loss of interest or pleasure in usual activities accompanied by sleep and appetite disturbances, agitation or lack of energy, feelings of guilt or worthlessness, decreased sex drive, inability to concentrate, and perhaps thoughts of suicide. Unlike the more familiar tricyclic antidepressants, such as Elavil, Tofranil, and others, Wellbutrin tends to have a somewhat stimulating effect.
The drug is available in regular and sustained-release formulations (Wellbutrin SR).
Most important fact about Wellbutrin
Although Wellbutrin occasionally causes weight gain, a more common effect is weight loss: Some 28 percent of people who take this medication lose 5 pounds or more. If depression has already caused you to lose weight, and if further weight loss would be detrimental to your health, Wellbutrin may not be the best antidepressant for you.
How should you take Wellbutrin?
Take Wellbutrin exactly as prescribed by your doctor. The usual dosing regimen is 3 equal doses spaced evenly throughout the day. Allow at least 6 hours between doses. Your doctor will probably start you at a low dosage and gradually increase it; this helps minimize side effects. You should take Wellbutrin SR, the sustained-release form, in 2 doses, at least 8 hours apart. Swallow Wellbutrin SR tablets whole; do not chew, divide, or crush them. If Wellbutrin works for you, your doctor will probably have you continue taking it for at least several months. --If you miss a dose...Take it as soon as you remember. If it is within 4 hours of your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time. --Storage instructions...
Store at room temperature. Protect from light and moisture.
What side effects may occur with Wellbutrin?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Wellbutrin. Seizures are perhaps the most worrisome side effect.
More common side effects may include:
Abdominal pain (Wellbutrin SR), agitation, anxiety (Wellbutrin SR), constipation, dizziness, dry mouth, excessive sweating, headache, loss of appetite (Wellbutrin SR), nausea, palpitations (Wellbutrin SR), vomiting, skin rash, sleep disturbances, sore throat (Wellbutrin SR), tremor
Other side effects may include:
Acne, allergic reactions (severe), bed-wetting, blisters in the mouth and eyes (Stevens-Johnson syndrome) blurred vision, breathing difficulty, chest pain, chills, complete or almost complete loss of movement, confusion, dry skin, episodes of over-activity, elation, or irritability, extreme calmness, fatigue, fever, fluid retention, flu-like symptoms, gum irritation and inflammation, hair color changes, hair loss, hives, impotence, incoordination and clumsiness, indigestion, itching, increased libido, menstrual complaints, mood instability, muscle rigidity, painful ejaculation, painful erection, retarded ejaculation, ringing in the ears, sexual dysfunction, suicidal ideation, thirst disturbances, toothache, urinary disturbances, weight gain or loss
Why should Wellbutrin not be prescribed?
Do not take Wellbutrin if you are sensitive to or have ever had an allergic reaction to it. Since Wellbutrin causes seizures in some people, do not take it if you have any type of seizure disorder or if you are taking another medication containing bupropion, such as Zyban, the quit smoking aid. If you have a seizure while taking Wellbutrin, stop taking the drug and never take it again. Do not take Wellbutrin while abruptly giving up alcohol or sedatives, including tranquilizers such as Librium, Valium, and Xanax. Rapid withdrawal increases the risk of seizures. If you have had any kind of heart trouble or liver or kidney disease, be sure your doctor knows about it before you start taking this drug. It must be used with extreme caution if you have severe cirrhosis of the liver. A reduced dosage may be needed if you have any sort of liver or kidney problem. You should not take Wellbutrin if you currently have, or formerly had, an eating disorder. For some reason, people with a history of anorexia nervosa or bulimia seem to be more likely to experience Wellbutrin-related seizures.
Do not take Wellbutrin if, within the past 14 days, you have taken a monoamine oxidase inhibitor (MAO inhibitor) drug, such as the antidepressants Marplan, Nardil or Parnate. Thisparticular drug combination could cause you to experience a sudden, dangerous rise in blood pressure.
Recommended dosage
No single dose of Wellbutrin should exceed 150 milligrams.
ADULTS
Wellbutrin At the beginning, your dose will probably be 200 milligrams per day, taken as 100 milligrams 2 times a day. After at least 3 days at this dose, your doctor may increase the dosage to 300 milligrams per day, taken as 100 milligrams 3 times a day, with at least 6 hours between doses. This is the usual adult dose. The maximum recommended dosage is 450 milligrams per day taken in doses of no more than 150 milligrams each. Wellbutrin SR The usual starting dose is 150 milligrams in the morning. After 3 days, if you do well, your doctor will have you take another 150 milligrams at least 8 hours after the first dose. It may be 4 weeks before you feel the benefit and you will take the drug for several months. The maximum recommended dose is 400 milligrams a day, taken in doses of 200 milligrams each. If you have severe cirrhosis of the liver, your dosage should be no more than 75 milligrams once a day. With less serious liver and kidney problems, the dosage will be somewhat reduced.
CHILDREN
The safety and effectiveness in children under 18 years old have not been established.
OLDER ADULTS
Although they are more sensitive to antidepressant drugs, older people have responded no differently to Wellbutrin than younger people.
Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose of Wellbutrin, seek medical attention immediately.
Symptoms of Wellbutrin overdose may include:
Hallucinations, heart failure, loss of consciousness, rapid heartbeat, seizures
Symptoms of Wellbutrin SR overdose may include:
Blurred vision, confusion, jitteriness, lethargy, light-headedness, nausea, seizures, vomiting
An overdose that involves other drugs in combination with Wellbutrin may also cause these symptoms:
Breathing difficulties, coma, fever, rigid muscles, stupor
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