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Zofran drug description and what Zofran is used to treat

Zofran is a selective 5-HT3 receptor antagonist which can effectively prevent nausea and vomiting. It is usually used after surgery where patients usually feel nauseated due to the effects of anesthesia. Zofran can also be used to prevent nausea and vomiting in patients undergoing chemotherapy. The drug acts by blocking a neurotransmitter called serotonin, which is the substance that causes vomiting.

In order to prevent nausea and vomiting, patients who will be undergoing chemotherapy should take Zofran 30 minutes before chemotherapy starts. In patients who will be undergoing radiation therapy, Zofran should be taken 1 to 2 hours prior to the treatment. For patients who are going to have surgery, Zofran may be advised to be taken 1 hour prior to surgery. The drug does not usually cause gastric irritation so it can be safely taken without food, but if the patient prefers to take it after meals, he or she may do so.

It is very important to ask the attending physician first before taking anything if the patient is to undergo chemotherapy, radiation therapy and surgery since some physicians may not allow the patient to take anything by mouth prior to these procedures because of the possible complications.

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