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Manufactured by GlaxoSmithKline Inc. Zyban is used to relieve symptoms of major depression. Bupropion is also used as a non-nicotine aid to smoking cessation. It should be used as a part of a comprehensive smoking cessation program carried out under the supervision of your doctor.
Zyban is a nicotine-free quit-smoking aid. Instead of nicotine, it contains the same active ingredient as the antidepressant medication Wellbutrin. It works by boosting the levels of several chemical messengers in the brain. With more of these chemicals at work, you experience a reduction in nicotine withdrawal symptoms and a weakening of the urge to smoke. More than a third of the people who take Zyban while participating in a support program are able to quit smoking for at least 1 month. Zyban can also prove helpful when people with conditions such as chronic bronchitis and emphysema decide it's time to quit.
Most important fact about Zyban
About 1 person in 1,000 suffers a seizure while taking Zyban. For this reason, people with epilepsy and certain other disorders should never take the drug. Don't share Zyban with friends. Only a doctor can decide whether it's safe for a particular individual.
Where can I order Zyban from? Can I buy Zyban at Canadian Prices?
Yes, if you are from the U.S. then you can buy Zyban at Canadian prices. Currently we will only accept an order for Zyban from U.S. and Canadian residents. Both U.S. and Canadian residents require a prescription to purchase Zyban and when you order Zyban it will be delivered with express shipping.
How should you take this Zyban?
Treatment with this drug begins while you are still smoking. Zyban needs about a week to reach an effective level in your body; so to improve your chance of success, you should not attempt to quit until the second week of treatment. Set a firm date for quitting. If you are still smoking after that date, your odds of breaking the habit will be worse. You should keep taking Zyban for 7 to 12 weeks. You can use nicotine patches along with Zyban. However, combining the two treatments can raise your blood pressure, so it's important to tell your doctor if you plan to use both. Do not smoke while using a patch, because too much nicotine can cause serious side effects. Participating in a counseling or support program will make success more likely. Your doctor can recommend a local program for you. Swallow Zyban tablets whole. Do not chew, divide, or crush them. Take them exactly as prescribed. --If you miss a dose...Do not take an extra tablet to "catch up" for the missed dose. Skip the dose and take your next tablet at the regularly scheduled time. --Storage instructions...
Store at room temperature in a tightly closed container. Keep out of direct sunlight.
What side effects may occur with Zyban?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zyban.
The most common side effects are:
Dry mouth and sleeplessness
These are generally mild and usually disappear after a few weeks. If you have difficulty sleeping, avoid taking Zyban close to bedtime and ask your doctor about reducing your dosage.
More common side effects may include:
Abdominal pain, abnormal dreams, anxiety, constipation, diarrhea, disturbed concentration, dizziness, joint pain, increased cough, itching, nasal inflammation, nausea, nervousness, rash, sore throat
Less common side effects may include:
Abnormal thinking, allergic reaction, bronchitis, changes in taste, difficulty breathing, dry skin, fever, hives, hot flashes, increased appetite or loss ofappetite, increased blood pressure, migraine, mouth ulcers, muscle pain, neck pain, nosebleed, ringing in the ears, shakiness, sinus inflammation, sleepiness, throbbing heartbeat
Rare side effects may include:
Chest pain, feeling of unhappiness, thirst, swelling of the face
Possible food and drug interactions
If Zyban is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zyban with the following:
Alcohol
Amantadine (Symmetrel)
Antidepressants such as Norpramin, Pamelor, Paxil, Prozac, Tofranil, and Zoloft
Beta blockers (heart and blood pressure medications) such as Inderal, Lopressor, and Tenormin
Carbamazepine (Tegretol)
Cimetidine (Tagamet)
Cyclophosphamide (Cytoxan)
Heart-stabilizing drugs such as Rythmol and Tambocor
Levodopa (Dopar, Larodopa, Sinemet)
Major tranquilizers such as Haldol, Risperdal and Thorazine
MAO inhibitors such as the antidepressants Nardil and Parnate
Orphenadrine (Norflex)
Phenobarbital
Phenytoin (Dilantin)
Steroids such as prednisone and hydrocortisone
Theophylline (Theo-Dur, Theolair)
Quitting smoking, with or without Zyban treatment, could change the way your body metabolizes certain drugs, for example, theophylline and warfarin (Coumadin). Make sure your doctor knows all the prescription and over the-counter medicines you're taking.
Recommended dosage
ADULTS The usual starting dose is one 150-milligram tablet in the morning for the first 3 days. After that, take one 150-milligram tablet in the morning and another in the early evening. Keep doses at least 8 hours apart. The maximum recommended dose is 300 milligrams daily.
Continue taking Zyban for 7 to 12 weeks. Your doctor may recommend continuing treatment for up to 6 months. Kidney and Liver Disease Your doctor may reduce the frequency of your doses to avoid high blood levels of Zyban. If you have severe cirrhosis of the liver, you should take no more than 150 milligrams every other day.
CHILDREN The safety and efficacy of Zyban have not been established in children under 18.
Overdosage
Information on Zyban overdose is limited. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.
Symptoms of Zyban overdose may include:
Blurred vision, confusion, grogginess, jitteriness, light-headedness, nausea, seizure, sluggishness, visual hallucinations
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